The annual Elsass Summer Lecture will be held by Professor John Cryan on the subject of ‘Microbiome as a Key Regulator of the Brain Across the Lifespan’.
In August 2019 Irish Professor John Cryan will hold the annual summer lecture at the Elsass Foundation in Charlottenlund. The lecture is open for everyone with an interest in neuroscience.
Professor John Cryan is from the Department of Anatomy & Neuroscience, University College Cork (UCC), Ireland, and he is the Principal Investigator at APC Microbiome Ireland.
The lecture will address the newest research concerning relations between brain, gut and microbiota.
Monday August 19, 2019
18:30 Lecture by Professor John Cryan
20:00 Snacks in the Living Rooms and Orangery
Registration is free but required, latest August 12’th. Seats are assigned on a first-come-first-served basis.
The brain-gut-microbiota axis is emerging as a research area of increasing interest for those investigating the biological and physiological basis of neurodevelopmental, age-related and neurodegenerative disorders. The routes of communication between the gut and brain include the vagus nerve, the immune system, tryptophan metabolism, via the enteric nervous system or by way of microbial metabolites such as short chain fatty acids.
Studies in animal models have been key in delineating that neurodevelopment and the programming of an appropriate stress response is dependent on the microbiota. Developmentally, a variety of factors can impact the microbiota in early life including mode of birth delivery, antibiotic exposure, mode of nutritional provision, infection, stress as well as host genetics.
At the other extreme of life, individuals who age with considerable ill health tend to show narrowing in microbial diversity. Stress can significantly impact the microbiota-gut-brain axis at all stages across the lifespan. Recently, the gut microbiota has been implicated in a variety of conditions including obesity, autism, schizophrenia and Parkinson’s disease. Moreover, animal models have been key in linking the regulation of fundamental brain processes ranging from adult hippocampal neurogenesis to myelination to microglia activation by the microbiome.
Finally, studies examining the translation of these effects from animals to humans are currently ongoing. Further studies will focus on understanding the mechanisms underlying such brain effects and developing nutritional and microbial-based intervention strategies.
About John Cryan
John F. Cryan is Professor & Chair, Dept. of Anatomy & Neuroscience, University College Cork (UCC), Ireland and is also a Principal Investigator at APC Microbiome Ireland. His research is focused on understanding the interaction between brain, gut & microbiome and how it applies to stress, psychiatric and immune-related disorders at key time-windows across the lifespan.
He received a B.Sc. (Hons) and PhD from the National University of Ireland, Galway, Ireland. He was a visiting fellow at the Dept Psychiatry, University of Melbourne, Australia (1997-1998), which was followed by postdoctoral fellowships at the University of Pennsylvania, Philadelphia, USA and The Scripps Research Institute, La Jolla, California.
He spent four years at the Novartis Institutes for BioMedical Research in Basel Switzerland, as a LabHead, Behavioural Pharmacology prior to joining UCC in 2005. Cryan has published over 470 papers and has a h-Index of 100. He is co-author of the bestselling “The Psychobiotic Revolution: Mood, Food, and the New Science of the Gut-Brain Connection”, was elected a Member of the Royal Irish Academy in 2017 and was awarded an Honorary Doctorate from the University of Antwerp, Belgium In 2018.
He has been a TEDMED & TEDx speaker and is currently President of the European Behavioural Pharmacology Society.